Journal: Annals of Translational Medicine
Article Title: Factorial design and post-antibiotic sub-MIC effects of linezolid combined with fosfomycin against vancomycin-resistant enterococci
doi: 10.21037/atm-21-4595
Figure Lengend Snippet: Summary of MIC and FICI values of the 8 enterococci strains
Article Snippet: The FICI values illustrated that linezolid combined with fosfomycin had a synergistic or an additive effect on the 6 strains, had an indifferent effect on the No. 1 and ATCC29212 strains, and did not have an antagonistic effect on any of the strains (see ). table ft1 table-wrap mode="anchored" t5 caption a7 Strains MIC (mg/L) MIC combination FICI VAN LNZ FOS LNZ/FOS LNZ + FOS No. 1 4 2 64 0.03125/64 1.015 No. 2 4 2 128 0.5/32 0.5 No. 3 2 2 128 1/32 0.75 No. 4 2 4 256 0.5/128 0.625 No. 5 1 4 128 1/32 0.5 No. 8 128 2 128 1/32 0.75 ATCC 29212 1 2 128 1/64 1 ATCC 51299 256 2 128 0.5/32 0.5 Open in a separate window VAN: ≤4 mg/L, susceptible (S); 8–16 mg/L, intermediate (I); ≥32 mg/L, resistant (R).
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